5′ UTR m(6)A Promotes Cap-Independent Translation

Protein translation typically begins with the recruitment of the 43S ribosomal complex to the 5′ cap of mRNAs by a cap-binding complex. However, some transcripts are translated in a cap-independent manner through poorly understood mechanisms. Here, we show that mRNAs containing N(6)-methyladenosine...

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Publicado en:Cell
Autores principales: Meyer, Kate D., Patil, Deepak P., Zhou, Jun, Zinoviev, Alexandra, Skabkin, Maxim A., Elemento, Olivier, Pestova, Tatyana V., Qian, Shu-Bing, Jaffrey, Samie R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695625/
https://ncbi.nlm.nih.gov/pubmed/26593424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.10.012
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