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Evaluation of the behavioral and pharmacokinetic profile of SYA013, a homopiperazine analogue of haloperidol in rats

SYA013, a homopiperazine analogue of haloperidol, was further evaluated for antipsychotic potential using additional animal models. Previously, SYA013 was tested in mice with an antipsychotic screening model in which it inhibited apomorphine induced climbing behavior, indicating antagonism of the do...

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Bibliografiske detaljer
Main Authors: Bricker, Barbara, Jackson, Tanise, Boateng, Bernard, Zhu, Xue Y., Ablordeppey, Seth Y.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383382/
https://ncbi.nlm.nih.gov/pubmed/22588199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2012.05.003
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