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SYA 013 analogs as sigma-2 (σ(2)) selective ligands: structure-affinity relationship studies

Several lines of evidence suggest that selective sigma-2 (σ(2)) ligands might be useful for the treatment of solid tumors. However, very few selective σ(2) ligands have been identified. This study was aimed at identifying new selective σ(2) receptor ligands using a previously identified agent, SYA 0...

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Publicat a:Bioorg Med Chem
Autors principals: Al-Ghanim, Lamya, Zhu, Xue Y., Asong, Gladys, Ablordeppey, Seth Y.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536313/
https://ncbi.nlm.nih.gov/pubmed/30737135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.01.035
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