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SYA 013 analogs as sigma-2 (σ(2)) selective ligands: structure-affinity relationship studies

Several lines of evidence suggest that selective sigma-2 (σ(2)) ligands might be useful for the treatment of solid tumors. However, very few selective σ(2) ligands have been identified. This study was aimed at identifying new selective σ(2) receptor ligands using a previously identified agent, SYA 0...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Al-Ghanim, Lamya, Zhu, Xue Y., Asong, Gladys, Ablordeppey, Seth Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536313/
https://ncbi.nlm.nih.gov/pubmed/30737135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2019.01.035
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