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The C-terminus of neuronal Kv2.1 channels is required for channel localization and targeting but not for NMDA-receptor mediated regulation of channel function
The delayed rectifier voltage-gated potassium channel Kv2.1 underlies a majority of the somatic K(+) current in neurons and is particularly important for regulating intrinsic neuronal excitability. Various stimuli alter Kv2.1 channel gating as well as localization of the channel to cell-surface clus...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383376/ https://ncbi.nlm.nih.gov/pubmed/22554782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.04.054 |
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