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The C-terminus of neuronal Kv2.1 channels is required for channel localization and targeting but not for NMDA-receptor mediated regulation of channel function

The delayed rectifier voltage-gated potassium channel Kv2.1 underlies a majority of the somatic K(+) current in neurons and is particularly important for regulating intrinsic neuronal excitability. Various stimuli alter Kv2.1 channel gating as well as localization of the channel to cell-surface clus...

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Autors principals: Baver, Scott B., O'Connell, Kristen M.S.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383376/
https://ncbi.nlm.nih.gov/pubmed/22554782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.04.054
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