Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice

Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related death. The biologic processes contributing to TRALI are poorly understood. All blood products can cause TRALI, and no specific treatment is available. A “2-event model” has been proposed as the trigger. The fir...

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Autori principali: Thomas, Grace M., Carbo, Carla, Curtis, Brian R., Martinod, Kimberly, Mazo, Irina B., Schatzberg, Daphne, Cifuni, Stephen M., Fuchs, Tobias A., von Andrian, Ulrich H., Hartwig, John H., Aster, Richard H., Wagner, Denisa D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2012
Soggetti:
Transfusion Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383196/
https://ncbi.nlm.nih.gov/pubmed/22596262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-405183
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