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Requirement of 3-Phosphoinositide-Dependent Protein Kinase-1 for BDNF-Mediated Neuronal Survival

Although PDK1 regulates several signaling pathways that respond to neurotrophins, direct evidence for its involvement in neurotrophin-mediated survival has not yet been reported. Here we show high neuronal expression of active PDK1 in the rat cortex and hippocampus at the developmental stages with p...

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Detalhes bibliográficos
Main Authors: Kharebava, Giorgi, Makonchuk, Denys, Kalita, Katarzyna B., Zheng, Jing-Juan, Hetman, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383049/
https://ncbi.nlm.nih.gov/pubmed/18971483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2135-08.2008
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