Phosphoinositide 3-Kinase Enhancer Regulates Neuronal Dendritogenesis and Survival in Neocortex

Phosphoinositide 3-kinase enhancer (PIKE) binds and enhances phosphatidylinositol 3-kinase (PI3K)/Akt activities. However, its physiological functions in brain have never been explored. Here we show that PIKE is important in regulating the neuronal survival and development of neocortex. During devel...

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Main Authors: Bun Chan, Chi, Liu, Xia, Pradoldej, Sompol, Hao, Chunhai, An, Jie, Yepes, Manuel, Luo, Hongbo R., Ye, Keqiang
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2011
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551346/
https://ncbi.nlm.nih.gov/pubmed/21632930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1129-11.2011
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