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The association of phosphoinositide 3-kinase enhancer A with hepatic insulin receptor enhances its kinase activity
Dysfunction of hepatic insulin receptor tyrosine kinase (IRTK) causes the development of type 2 diabetes. However, the molecular mechanism regulating IRTK activity in the liver remains poorly understood. Here, we show that phosphoinositide 3-kinase enhancer A (PIKE-A) is a new insulin-dependent enha...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3147257/ https://ncbi.nlm.nih.gov/pubmed/21720388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.108 |
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