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The differential production of cytokines by human Langerhans cells and dermal CD14(+) DCs controls CTL priming

We recently reported that human epidermal Langerhans cells (LCs) are more efficient than dermal CD14(+) DCs at priming naive CD8(+) T cells into potent CTLs. We hypothesized that distinctive dendritic cell (DC) cytokine expression profiles (ie, IL-15 produced by LCs and IL-10 expressed by dermal CD1...

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Main Authors: Banchereau, Jacques, Thompson-Snipes, LuAnn, Zurawski, Sandra, Blanck, Jean-Philippe, Cao, Yanying, Clayton, Sandra, Gorvel, Jean-Pierre, Zurawski, Gerard, Klechevsky, Eynav
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382933/
https://ncbi.nlm.nih.gov/pubmed/22535664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-371245
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