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Breaking the tolerance for tumor: Targeting negative regulators of TLR signaling
Tumors arise and progress in immunocompetent hosts presumably by activating tolerance mechanisms critical for normal homeostasis. Host immune cells can mount anti-tumor responses by activation of Toll-like receptors (TLRs). However, emerging data suggests that molecules that negatively regulate TLRs...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Landes Bioscience
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382869/ https://ncbi.nlm.nih.gov/pubmed/22737610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.18434 |
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