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The combination of histone deacetylase inhibitors with immune-stimulating antibodies has potent anti-cancer effects

The use of immunotherapy to treat cancer is rapidly gaining momentum. Using pre-clinical mouse models, we have recently demonstrated potent and long lasting tumor regression can be elicited by immune-stimulating monoclonal antibodies (mAbs) when combined with histone deacetylase inhibitors (HDACi) a...

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Autors principals: West, Alison C., Christiansen, Ailsa J., Smyth, Mark J., Johnstone, Ricky W.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382866/
https://ncbi.nlm.nih.gov/pubmed/22737621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.18804
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