Cooperativity in long-range gene regulation by the λ CI repressor

Effective repression of cI transcription from P(RM) by the bacteriophage λ CI repressor requires binding sites (O(L)) located 2.4 kb from the promoter. A CI tetramer bound to O(L)1.O(L)2 interacts with a tetramer bound near P(RM) (O(R)1.O(R)2), looping the intervening DNA. We previously proposed tha...

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Main Authors: Dodd, Ian B., Shearwin, Keith E., Perkins, Alison J., Burr, Tom, Hochschild, Ann, Egan, J. Barry
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2004
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Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC338286/
https://ncbi.nlm.nih.gov/pubmed/14871931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1167904
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