載入...
Chronic activation of DNA damage signals causes tumor immune evasion in the chemoresistant niche
DNA damage responses have been proposed as a gatekeeper to block tumorigenesis. We identify unexpected mechanisms whereby ATM-mediated pathway interacts with NFκB inflammatory cascades, leading to upregulation of integrin-αbβ3 on chemoresistant tumor cells. The integrin-αbβ3 is responsible for imped...
Na minha lista:
| 主要作者: | |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2012
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382849/ https://ncbi.nlm.nih.gov/pubmed/22737630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.19123 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|