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Nano-Advantage in Enhanced Drug Delivery with Biodegradable Nanoparticles: Contribution of Reduced Clearance

The aim of this study was to investigate the contribution of reduced apparent clearance to the enhanced exposure reported for biodegradable nanoparticles after extravascular and intravascular routes of administration. Plasma concentration profiles for drug and nanoparticle formulations after adminis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kadam, Rajendra S., Bourne, David W. A., Kompella, Uday B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382836/
https://ncbi.nlm.nih.gov/pubmed/22498894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.044925
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