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Nano-Advantage in Enhanced Drug Delivery with Biodegradable Nanoparticles: Contribution of Reduced Clearance

The aim of this study was to investigate the contribution of reduced apparent clearance to the enhanced exposure reported for biodegradable nanoparticles after extravascular and intravascular routes of administration. Plasma concentration profiles for drug and nanoparticle formulations after adminis...

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Bibliografiske detaljer
Main Authors: Kadam, Rajendra S., Bourne, David W. A., Kompella, Uday B.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382836/
https://ncbi.nlm.nih.gov/pubmed/22498894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.044925
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