Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation

The checkpoint kinase ATM is centrally involved in the cellular response to DNA double-strand breaks. However, the mechanism of ATM activation during genotoxicstress is only partially understood. Here we report a direct regulatory linkage between the protein serine-threonine phosphatase 5 (PP5) and...

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Bibliographic Details
Main Authors: Ali, Ambereen, Zhang, Ji, Bao, Shideng, Liu, Irene, Otterness, Diane, Dean, Nicholas M., Abraham, Robert T., Wang, Xiao-Fan
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2004
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC338278/
https://ncbi.nlm.nih.gov/pubmed/14871926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1176004
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