Blocking Fibroblast Growth Factor Receptor Signaling Inhibits Tumor Growth, Lymphangiogenesis, and Metastasis

Fibroblast Growth Factor receptor (FGFR) activity plays crucial roles in tumor growth and patient survival. However, FGF (Fibroblast Growth Factor) signaling as a target for cancer therapy has been under-investigated compared to other receptor tyrosine kinases. Here, we studied the effect of FGFR si...

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Bibliografiske detaljer
Main Authors: Larrieu-Lahargue, Frédéric, Welm, Alana L., Bouchecareilh, Marion, Alitalo, Kari, Li, Dean Y., Bikfalvi, Andreas, Auguste, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382584/
https://ncbi.nlm.nih.gov/pubmed/22761819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039540
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