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Blocking Fibroblast Growth Factor Receptor Signaling Inhibits Tumor Growth, Lymphangiogenesis, and Metastasis

Fibroblast Growth Factor receptor (FGFR) activity plays crucial roles in tumor growth and patient survival. However, FGF (Fibroblast Growth Factor) signaling as a target for cancer therapy has been under-investigated compared to other receptor tyrosine kinases. Here, we studied the effect of FGFR si...

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Detalhes bibliográficos
Main Authors: Larrieu-Lahargue, Frédéric, Welm, Alana L., Bouchecareilh, Marion, Alitalo, Kari, Li, Dean Y., Bikfalvi, Andreas, Auguste, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382584/
https://ncbi.nlm.nih.gov/pubmed/22761819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039540
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