Blocking Fibroblast Growth Factor Receptor Signaling Inhibits Tumor Growth, Lymphangiogenesis, and Metastasis

Fibroblast Growth Factor receptor (FGFR) activity plays crucial roles in tumor growth and patient survival. However, FGF (Fibroblast Growth Factor) signaling as a target for cancer therapy has been under-investigated compared to other receptor tyrosine kinases. Here, we studied the effect of FGFR si...

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Autors principals: Larrieu-Lahargue, Frédéric, Welm, Alana L., Bouchecareilh, Marion, Alitalo, Kari, Li, Dean Y., Bikfalvi, Andreas, Auguste, Patrick
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382584/
https://ncbi.nlm.nih.gov/pubmed/22761819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039540
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