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Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis
Use of long-term constitutive expression of VEGF for therapeutic angiogenesis may be limited by the growth of abnormal blood vessels and hemangiomas. We investigated the relationship between VEGF dosage and the morphology and function of newly formed blood vessels by implanting retrovirally transduc...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC338257/ https://ncbi.nlm.nih.gov/pubmed/14966561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200418420 |
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