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Microenvironmental VEGF concentration, not total dose, determines a threshold between normal and aberrant angiogenesis

Use of long-term constitutive expression of VEGF for therapeutic angiogenesis may be limited by the growth of abnormal blood vessels and hemangiomas. We investigated the relationship between VEGF dosage and the morphology and function of newly formed blood vessels by implanting retrovirally transduc...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ozawa, Clare R., Banfi, Andrea, Glazer, Nicole L., Thurston, Gavin, Springer, Matthew L., Kraft, Peggy E., McDonald, Donald M., Blau, Helen M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC338257/
https://ncbi.nlm.nih.gov/pubmed/14966561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200418420
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