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Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA-Myosin II signaling

The organization of the apical junctional complex and its association with the cytoskeleton is essential for the function of epithelial cells. However, knowledge about the signaling pathways that regulate these processes is still fragmentary. Here we found that ARHGEF11, a member of the RGS-RhoGEF f...

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Detalhes bibliográficos
Main Authors: Itoh, Masahiko, Tsukita, Sachiko, Yamazaki, Yuji, Sugimoto, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382488/
https://ncbi.nlm.nih.gov/pubmed/22665792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115063109
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