Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis

Abnormal activity of the renin-angiotensin-aldosterone system plays a causal role in the development of hypertension, atherosclerosis, and associated cardiovascular events such as myocardial infarction, stroke, and heart failure. As both a vasoconstrictor and a proinflammatory mediator, angiotensin...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Carbone, Maria Luigia, Chadeuf, Gilliane, Heurtebise-Chrétien, Sandrine, Prieur, Xavier, Quillard, Thibault, Goueffic, Yann, Vaillant, Nathalie, Rio, Marc, Castan, Laure, Durand, Maxim, Baron-Menguy, Céline, Aureille, Julien, Desfrançois, Juliette, Tesse, Angela, Torres, Raul M., Loirand, Gervaise
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707138/
https://ncbi.nlm.nih.gov/pubmed/29130930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92702
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