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RhoA Phosphorylation Induces Rac1 Release from Guanine Dissociation Inhibitor α and Stimulation of Vascular Smooth Muscle Cell Migration

Although overactivation of RhoA is recognized as a common component of vascular disorders, the molecular mechanisms regulating RhoA activity in vascular smooth muscle cells (VSMC) are still unclear. We have previously shown that in VSMC, RhoA is phosphorylated on Ser188 by nitric oxide (NO)-stimulat...

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Hlavní autoři: Rolli-Derkinderen, Malvyne, Toumaniantz, Gilles, Pacaud, Pierre, Loirand, Gervaise
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950537/
https://ncbi.nlm.nih.gov/pubmed/20696841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00381-10
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