Upregulation of proteasome activity in muscle RING finger 1-null mice following denervation

Deletion of muscle RING finger 1 (MuRF1), an E3 ubiquitin ligase, leads to sparing of muscle mass following denervation. The purpose of this study was to test the hypothesis that muscle sparing in mice with a deletion of MuRF1 is due to the selective inhibition of the ubiquitin proteasome system. Ac...

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Detalhes bibliográficos
Main Authors: Gomes, Aldrin V., Waddell, Dave S., Siu, Rylie, Stein, Matthew, Dewey, Shannamar, Furlow, J. David, Bodine, Sue C.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2012
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382096/
https://ncbi.nlm.nih.gov/pubmed/22508689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-204495
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