Maintenance of muscle mass and load-induced growth in Muscle RING Finger 1 null mice with age

Age-related loss of muscle mass occurs to varying degrees in all individuals and has a detrimental effect on morbidity and mortality. Muscle RING Finger 1 (MuRF1), a muscle-specific E3 ubiquitin ligase, is believed to mediate muscle atrophy through the ubiquitin proteasome system (UPS). Deletion of...

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Bibliographische Detailangaben
Hauptverfasser: Hwee, Darren T, Baehr, Leslie M, Philp, Andrew, Baar, Keith, Bodine, Sue C
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947038/
https://ncbi.nlm.nih.gov/pubmed/23941502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12150
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