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Cardiac proteasome activity in muscle ring finger-1 null mice at rest and following synthetic glucocorticoid treatment

Muscle ring finger-1 (MuRF1) is a muscle-specific E3 ubiquitin ligase that has been implicated in the regulation of cardiac mass through its control of the ubiquitin proteasome system. While it has been suggested that MuRF1 is required for cardiac atrophy, a resting cardiac phenotype has not been re...

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Autores principales: Hwee, Darren T., Gomes, Aldrin V., Bodine, Sue C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214003/
https://ncbi.nlm.nih.gov/pubmed/21828340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00165.2011
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