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CD8(+) FOXP3(+) REGULATORY T CELLS ARE INDUCED DURING GRAFT VERSUS HOST DISEASE AND MITIGATE DISEASE SEVERITY

Regulatory T cells (Tregs), in particular CD4(+) Foxp3(+) T cells, have been shown to play an important role in the maintenance of tolerance after allogeneic stem cell transplantation. In the current study, we have identified a population of CD8(+) Foxp3(+) T cells that are induced early during GVHD...

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Detalhes bibliográficos
Main Authors: Beres, Amy J., Haribhai, Dipica, Chadwick, Alexandra C., Gonyo, Patrick J., Williams, Calvin B., Drobyski, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381996/
https://ncbi.nlm.nih.gov/pubmed/22649199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200886
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