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INSTABILITY OF FOXP3 EXPRESSION LIMITS THE ABILITY OF INDUCED REGULATORY T CELLS TO MITIGATE GRAFT VERSUS HOST DISEASE
PURPOSE: Graft versus host disease is the major complication of allogeneic bone marrow transplantation and limits the therapeutic efficacy of this modality. While the role of natural regulatory T cells (nTregs) in attenuating GVHD has been extensively examined, the ability of induced regulatory T ce...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117905/ https://ncbi.nlm.nih.gov/pubmed/21558402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-3347 |
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