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SEQCHIP: a powerful method to integrate sequence and genotype data for the detection of rare variant associations

Motivation: Next-generation sequencing greatly increases the capacity to detect rare-variant complex-trait associations. However, it is still expensive to sequence a large number of samples and therefore often small datasets are used. Given cost constraints, a potentially more powerful two-step stra...

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書目詳細資料
Main Authors: Liu, Dajiang J., Leal, Suzanne M.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381973/
https://ncbi.nlm.nih.gov/pubmed/22556370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts263
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