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SEQCHIP: a powerful method to integrate sequence and genotype data for the detection of rare variant associations
Motivation: Next-generation sequencing greatly increases the capacity to detect rare-variant complex-trait associations. However, it is still expensive to sequence a large number of samples and therefore often small datasets are used. Given cost constraints, a potentially more powerful two-step stra...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3381973/ https://ncbi.nlm.nih.gov/pubmed/22556370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts263 |
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