A novel variational Bayes multiple locus Z-statistic for genome-wide association studies with Bayesian model averaging

Motivation: For many complex traits, including height, the majority of variants identified by genome-wide association studies (GWAS) have small effects, leaving a significant proportion of the heritable variation unexplained. Although many penalized multiple regression methodologies have been propos...

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Bibliographic Details
Main Authors: Logsdon, Benjamin A., Carty, Cara L., Reiner, Alexander P., Dai, James Y., Kooperberg, Charles
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Original Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381972/
https://ncbi.nlm.nih.gov/pubmed/22563072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts261
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