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Effects of N-Acetylaspartylglutamate (NAAG) Peptidase Inhibition on Release of Glutamate and Dopamine in Prefrontal Cortex and Nucleus Accumbens in Phencyclidine Model of Schizophrenia

The “glutamate” theory of schizophrenia emerged from the observation that phencyclidine (PCP), an open channel antagonist of the NMDA subtype of glutamate receptor, induces schizophrenia-like behaviors in humans. PCP also induces a complex set of behaviors in animal models of this disorder. PCP also...

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Autori principali: Zuo, Daiying, Bzdega, Tomasz, Olszewski, Rafal T., Moffett, John R., Neale, Joseph H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381140/
https://ncbi.nlm.nih.gov/pubmed/22570482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.363226
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