Effects of Leptin and Melanocortin Signaling Interactions on Pubertal Development and Reproduction

Leptin and melanocortin signaling control ingestive behavior, energy balance, and substrate utilization, but only leptin signaling defects cause hypothalamic hypogonadism and infertility. Although GnRH neurons do not express leptin receptors, leptin influences GnRH neuron activity via regulation of...

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Autors principals: Israel, Davelene D., Sheffer-Babila, Sharone, de Luca, Carl, Jo, Young-Hwan, Liu, Shun Mei, Xia, Qiu, Spergel, Daniel J., Dun, Siok L., Dun, Nae J., Chua, Streamson C.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2012
Matèries:
Neuroendocrinology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381095/
https://ncbi.nlm.nih.gov/pubmed/22408174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1822
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