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Polyfunctional Type-1, -2, and -17 CD8(+) T Cell Responses to Apoptotic Self-Antigens Correlate with the Chronic Evolution of Hepatitis C Virus Infection
Caspase-dependent cleavage of antigens associated with apoptotic cells plays a prominent role in the generation of CD8(+) T cell responses in various infectious diseases. We found that the emergence of a large population of autoreactive CD8(+) T effector cells specific for apoptotic T cell-associate...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3380931/ https://ncbi.nlm.nih.gov/pubmed/22737070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002759 |
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