Increased CD8(+) T cell responses to apoptotic T cell-associated antigens in multiple sclerosis

BACKGROUND: Here, we evaluated the hypothesis that CD8(+) T cell responses to caspase-cleaved antigens derived from effector T cells undergoing apoptosis, may contribute to multiple sclerosis (MS) immunopathology. METHODS: The percentage of autoreactive CD8(+) T effector cells specific for various a...

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Detalhes bibliográficos
Main Authors: Lolli, Francesco, Martini, Helene, Citro, Alessandra, Franceschini, Debora, Portaccio, Emilio, Amato, Maria Pia, Mechelli, Rosella, Annibali, Viviana, Sidney, John, Sette, Alessandro, Salvetti, Marco, Barnaba, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734107/
https://ncbi.nlm.nih.gov/pubmed/23890271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-94
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