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Polyfunctional Type-1, -2, and -17 CD8(+) T Cell Responses to Apoptotic Self-Antigens Correlate with the Chronic Evolution of Hepatitis C Virus Infection

Caspase-dependent cleavage of antigens associated with apoptotic cells plays a prominent role in the generation of CD8(+) T cell responses in various infectious diseases. We found that the emergence of a large population of autoreactive CD8(+) T effector cells specific for apoptotic T cell-associate...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Franceschini, Debora, Del Porto, Paola, Piconese, Silvia, Trella, Emanuele, Accapezzato, Daniele, Paroli, Marino, Morrone, Stefania, Piccolella, Enza, Spada, Enea, Mele, Alfonso, Sidney, John, Sette, Alessandro, Barnaba, Vincenzo
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Public Library of Science 2012
الموضوعات:	Research Article
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3380931/ https://ncbi.nlm.nih.gov/pubmed/22737070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002759
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Polyfunctional Type-1, -2, and -17 CD8(+) T Cell Responses to Apoptotic Self-Antigens Correlate with the Chronic Evolution of Hepatitis C Virus Infection

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