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M-opsin protein degradation is inhibited by MG-132 in Rpe65(−/−) retinal explant culture
PURPOSE: The 65 kDa retinal pigment epithelium-specific protein, RPE65, is an essential enzyme for 11-cis-retinal synthesis in the eye. Mutations of the RPE65 gene in humans result in severe vision loss, and Rpe65(−/−) mice show early cone photoreceptor degeneration. We used an explant culture syste...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Molecular Vision
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3380917/ https://ncbi.nlm.nih.gov/pubmed/22736942 |
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