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Delivery of Topically Applied Calpain Inhibitory Peptide to the Posterior Segment of the Rat Eye
We developed an inhibitory peptide that specifically acts against mitochondrial μ-calpain (Tat-μCL, 23 amino acid, 2857.37 Da) and protects photoreceptors in retinal dystrophic rats. In the present study, we topically administered Tat-μCL to the eyes of Sprague-Dawley rats for 7 days to determine bo...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4479448/ https://ncbi.nlm.nih.gov/pubmed/26107400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130986 |
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