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Explant cultures of Rpe65(−/−) mouse retina: a model to investigate cone opsin trafficking

PURPOSE: In the absence of 11-cis retinal (e.g., Rpe65(−/−)), the chromophore for all pigments, cone opsins are mislocalized in vivo. Using the systemic application of 11-cis retinal, appropriate protein localization can be promoted. Here, we asked whether explant cultures of Rpe65(−/−) mouse retina...

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Main Authors: Bandyopadhyay, Mausumi, Kono, Masahiro, Rohrer, Bärbel
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Vision 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669539/
https://ncbi.nlm.nih.gov/pubmed/23734084
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