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YC-1 targeting of hypoxia-inducible factor-1α reduces RGC-5 cell viability and inhibits cell proliferation

PURPOSE: The survival of retinal ganglion cells (RGCs) is a hallmark of many optic neurodegenerative diseases such as glaucoma. YC-1, a potential anticancer drug, is known to be able to decrease the stability and protein expression of hypoxia-inducible factor (HIF)-1α that is triggered by hypoxia an...

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Bibliografski detalji
Glavni autori: Tsui, Leo, Fong, Tsorng-Harn, Wang, I-Jong
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380911/
https://ncbi.nlm.nih.gov/pubmed/22736948
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