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Hypoxia-inducible factor-1α antagonizes the hypoxia-mediated osteoblast cell viability reduction by inhibiting apoptosis

Bone fracture is accompanied with poor oxygen supply and nutrient deficiency in the local fracture site, and oxygen supply is an important factor that can affect fracture healing. Hypoxia-inducible factor-1 (HIF-1) plays a key role in the regulation of oxygen homeostasis. HIF-1α is rapidly upregulat...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: XU, GUICUN, XUE, MINGMING, WANG, HAIYAN, XIANG, CHUN
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471738/
https://ncbi.nlm.nih.gov/pubmed/26136896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2015.2319
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