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The effect of 3-(5′-hydroxymethyl-2’-furyl)-1-benzylindazole (YC-1) on cell viability under hypoxia

PURPOSE: The synthetic compound 3-(5′-hydroxymethyl-2’-furyl)-1-benzylindazole (YC-1) reduces the protein stability of hypoxia-inducible factor (HIF)-1α and can serve as a potential anticancer agent. Our previous study elucidated that YC-1 decreased the protein level of HIF-1α and inhibited cell pro...

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Autori principali: Tsui, Leo, Fong, Tsorng-Harn, Wang, I-Jong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Molecular Vision 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834593/
https://ncbi.nlm.nih.gov/pubmed/24265542
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