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Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis

Exposure to retinoids for the treatment of acne has been linked to the etiology of inflammatory bowel disease (IBD). The intestinal mucus layer is an important structural barrier that is disrupted in IBD. Retinoid-induced alteration of mucus physiology has been postulated as a mechanism linking reti...

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Autores principales: Oehlers, Stefan H., Flores, Maria Vega, Hall, Christopher J., Crosier, Kathryn E., Crosier, Philip S.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Limited 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380709/
https://ncbi.nlm.nih.gov/pubmed/22563081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.009365
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