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Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis

Exposure to retinoids for the treatment of acne has been linked to the etiology of inflammatory bowel disease (IBD). The intestinal mucus layer is an important structural barrier that is disrupted in IBD. Retinoid-induced alteration of mucus physiology has been postulated as a mechanism linking reti...

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Bibliografiske detaljer
Main Authors: Oehlers, Stefan H., Flores, Maria Vega, Hall, Christopher J., Crosier, Kathryn E., Crosier, Philip S.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Limited 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380709/
https://ncbi.nlm.nih.gov/pubmed/22563081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.009365
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