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A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation
By performing two high-content small molecule screens on DSS- and TNBS-induced zebrafish enterocolitis models of inflammatory bowel disease, we have identified novel anti-inflammatory drugs from the John Hopkins Clinical Compound Library that suppress neutrophilic inflammation. Live imaging of neutr...
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Publicado no: | FEBS J |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5296212/ https://ncbi.nlm.nih.gov/pubmed/27885812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13976 |
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