Pathology after Eculizumab in Dense Deposit Disease and C3 GN

Eculizumab might benefit C3 glomerulopathies mediated by dysregulation of the alternative complement pathway. Here, we report renal biopsy findings before and after eculizumab therapy in three patients with dense deposit disease and two with C3 GN. All pretreatment biopsies had glomerular and tubula...

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Autors principals: Herlitz, Leal C., Bomback, Andrew S., Markowitz, Glen S., Stokes, M. Barry, Smith, R. Neal, Colvin, Robert B., Appel, Gerald B., D’Agati, Vivette D.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2012
Matèries:
Clinical Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380652/
https://ncbi.nlm.nih.gov/pubmed/22677550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011121186
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