Pathology after Eculizumab in Dense Deposit Disease and C3 GN

Eculizumab might benefit C3 glomerulopathies mediated by dysregulation of the alternative complement pathway. Here, we report renal biopsy findings before and after eculizumab therapy in three patients with dense deposit disease and two with C3 GN. All pretreatment biopsies had glomerular and tubula...

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Bibliografski detalji
Glavni autori: Herlitz, Leal C., Bomback, Andrew S., Markowitz, Glen S., Stokes, M. Barry, Smith, R. Neal, Colvin, Robert B., Appel, Gerald B., D’Agati, Vivette D.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2012
Teme:
Clinical Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380652/
https://ncbi.nlm.nih.gov/pubmed/22677550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011121186
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