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Nedd4-2 and the Regulation of Epithelial Sodium Transport

Nedd4-2 is a ubiquitin ligase previously demonstrated to regulate endocytosis and lysosomal degradation of the epithelial Na(+) channel (ENaC) and other ion channels and transporters. Recent studies using Nedd4-2 knockout mice specifically in kidney or lung epithelia has revealed a critical role for...

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Bibliografiske detaljer
Main Authors: Rotin, Daniela, Staub, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Research Foundation 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380336/
https://ncbi.nlm.nih.gov/pubmed/22737130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00212
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