Hepatic Src Homology Phosphatase 2 Regulates Energy Balance in Mice

The Src homology 2 domain-containing protein-tyrosine phosphatase Src homology phosphatase 2 (Shp2) is a negative regulator of hepatic insulin action in mice fed regular chow. To investigate the role of hepatic Shp2 in lipid metabolism and energy balance, we determined the metabolic effects of its d...

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Hauptverfasser: Nagata, Naoto, Matsuo, Kosuke, Bettaieb, Ahmed, Bakke, Jesse, Matsuo, Izumi, Graham, James, Xi, Yannan, Liu, Siming, Tomilov, Alexey, Tomilova, Natalia, Gray, Susan, Jung, Dae Young, Ramsey, Jon J., Kim, Jason K., Cortopassi, Gino, Havel, Peter J., Haj, Fawaz G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2012
Schlagworte:
Energy Balance-Obesity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380313/
https://ncbi.nlm.nih.gov/pubmed/22619361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1406
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