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Hepatic Src Homology Phosphatase 2 Regulates Energy Balance in Mice

The Src homology 2 domain-containing protein-tyrosine phosphatase Src homology phosphatase 2 (Shp2) is a negative regulator of hepatic insulin action in mice fed regular chow. To investigate the role of hepatic Shp2 in lipid metabolism and energy balance, we determined the metabolic effects of its d...

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Autori principali: Nagata, Naoto, Matsuo, Kosuke, Bettaieb, Ahmed, Bakke, Jesse, Matsuo, Izumi, Graham, James, Xi, Yannan, Liu, Siming, Tomilov, Alexey, Tomilova, Natalia, Gray, Susan, Jung, Dae Young, Ramsey, Jon J., Kim, Jason K., Cortopassi, Gino, Havel, Peter J., Haj, Fawaz G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380313/
https://ncbi.nlm.nih.gov/pubmed/22619361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1406
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