Hepatic Src Homology Phosphatase 2 Regulates Energy Balance in Mice

The Src homology 2 domain-containing protein-tyrosine phosphatase Src homology phosphatase 2 (Shp2) is a negative regulator of hepatic insulin action in mice fed regular chow. To investigate the role of hepatic Shp2 in lipid metabolism and energy balance, we determined the metabolic effects of its d...

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Detalhes bibliográficos
Main Authors: Nagata, Naoto, Matsuo, Kosuke, Bettaieb, Ahmed, Bakke, Jesse, Matsuo, Izumi, Graham, James, Xi, Yannan, Liu, Siming, Tomilov, Alexey, Tomilova, Natalia, Gray, Susan, Jung, Dae Young, Ramsey, Jon J., Kim, Jason K., Cortopassi, Gino, Havel, Peter J., Haj, Fawaz G.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Energy Balance-Obesity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380313/
https://ncbi.nlm.nih.gov/pubmed/22619361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1406
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